東(dong)明縣(xian)第一(yi)中(zhong)(zhong)學初名“東(dong)明縣(xian)初級中(zhong)(zhong)學”，誕生于1951年，校址在縣(xian)城西北雙井村。是年秋，遷至縣(xian)城內(nei)東(dong)大(da)街文廟(miao)。 再名“東(dong)明縣(xian)完全中(zhong)(zhong)學”，時于1956年，開始招高中(zhong)(zhong)班。
2014年11月21日“山東(dong)(dong)師范(fan)大學(xue)附(fu)屬中(zhong)學(xue)東(dong)(dong)明(ming)合(he)作學(xue)校”的揭牌，標志著山東(dong)(dong)師范(fan)大學(xue)與東(dong)(dong)明(ming)縣教育合(he)作進入到(dao)了具體實施階段。
2002年(nian)(nian)(nian)東明一(yi)(yi)中(zhong)(zhong)學(xue)(xue)生(sheng)男(nan)子籃球(qiu)隊在全市重點(dian)中(zhong)(zhong)學(xue)(xue)籃球(qiu)比賽(sai)中(zhong)(zhong)獲(huo)冠軍，2003年(nian)(nian)(nian)該(gai)校(xiao)有8 名學(xue)(xue)生(sheng)被重點(dian)體(ti)育(yu)(yu)(yu)院校(xiao)特招。2003年(nian)(nian)(nian)該(gai)校(xiao)承辦市重點(dian)中(zhong)(zhong)學(xue)(xue)排球(qiu)運動會，男(nan)、女隊均獲(huo)亞軍。1998 年(nian)(nian)(nian)、2004年(nian)(nian)(nian)該(gai)校(xiao)體(ti)育(yu)(yu)(yu)高考錄取率均為(wei)全市第(di)一(yi)(yi)。東明一(yi)(yi)中(zhong)(zhong)先(xian)(xian)后被評為(wei)山(shan)(shan)東省(sheng)(sheng)衛生(sheng)先(xian)(xian)進單位(wei)，山(shan)(shan)東省(sheng)(sheng)電(dian)化(hua)教(jiao)育(yu)(yu)(yu)先(xian)(xian)進單位(wei)，菏澤市精神文明建(jian)設(she)先(xian)(xian)進單位(wei)，青少年(nian)(nian)(nian)工作(zuo)先(xian)(xian)進單位(wei)。2003年(nian)(nian)(nian)被評選為(wei)全國教(jiao)育(yu)(yu)(yu)科學(xue)(xue)“十(shi)五”規劃(hua)國家重點(dian)課題一(yi)(yi)一(yi)(yi)整體(ti)構建(jian)學(xue)(xue)校(xiao)德育(yu)(yu)(yu)體(ti)系深(shen)化(hua)研究與(yu)推廣實驗先(xian)(xian)進實驗學(xue)(xue)校(xiao)，又被山(shan)(shan)東省(sheng)(sheng)教(jiao)科所批準(zhun)為(wei)“心理教(jiao)育(yu)(yu)(yu)實驗基(ji)地”。2004年(nian)(nian)(nian)4月被確定為(wei)國家基(ji)礎教(jiao)育(yu)(yu)(yu)中(zhong)(zhong)心外語研究中(zhong)(zhong)心外語實驗學(xue)(xue)校(xiao)。 2004年(nian)(nian)(nian)7月，東明一(yi)(yi)中(zhong)(zhong)榮升(sheng)第(di)十(shi)一(yi)(yi)批省(sheng)(sheng)級規范化(hua)學(xue)(xue)校(xiao)。2005年(nian)(nian)(nian)學(xue)(xue)校(xiao)興建(jian)室(shi)內籃球(qiu)場和綜合辦公(gong)樓,師資力量進一(yi)(yi)步擴大。
2014年11月21日，“山(shan)(shan)東(dong)(dong)(dong)(dong)師(shi)(shi)(shi)(shi)范(fan)大(da)(da)學(xue)(xue)(xue)(xue)(xue)附屬(shu)中學(xue)(xue)(xue)(xue)(xue)東(dong)(dong)(dong)(dong)明(ming)(ming)(ming)(ming)合(he)作(zuo)學(xue)(xue)(xue)(xue)(xue)校(xiao)(xiao)”揭(jie)牌儀式在(zai)東(dong)(dong)(dong)(dong)明(ming)(ming)(ming)(ming)一(yi)(yi)中隆重舉行。山(shan)(shan)東(dong)(dong)(dong)(dong)師(shi)(shi)(shi)(shi)范(fan)大(da)(da)學(xue)(xue)(xue)(xue)(xue)附屬(shu)中學(xue)(xue)(xue)(xue)(xue)校(xiao)(xiao)長(chang)王玉璋、黨委(wei)書記(ji)譚英海、教(jiao)科研室主(zhu)任(ren)暨東(dong)(dong)(dong)(dong)明(ming)(ming)(ming)(ming)合(he)作(zuo)學(xue)(xue)(xue)(xue)(xue)校(xiao)(xiao)執行校(xiao)(xiao)長(chang)田明(ming)(ming)(ming)(ming)泉，山(shan)(shan)東(dong)(dong)(dong)(dong)師(shi)(shi)(shi)(shi)范(fan)大(da)(da)學(xue)(xue)(xue)(xue)(xue)駐(zhu)菜園集鎮第一(yi)(yi)書記(ji)杜朝偉、馬洪臣與東(dong)(dong)(dong)(dong)明(ming)(ming)(ming)(ming)縣(xian)主(zhu)要領(ling)導，教(jiao)育(yu)(yu)局、縣(xian)一(yi)(yi)中部分師(shi)(shi)(shi)(shi)生代(dai)表共同參加揭(jie)牌儀式。山(shan)(shan)東(dong)(dong)(dong)(dong)師(shi)(shi)(shi)(shi)范(fan)大(da)(da)學(xue)(xue)(xue)(xue)(xue)附屬(shu)中學(xue)(xue)(xue)(xue)(xue)東(dong)(dong)(dong)(dong)明(ming)(ming)(ming)(ming)合(he)作(zuo)學(xue)(xue)(xue)(xue)(xue)校(xiao)(xiao)的產生是(shi)山(shan)(shan)東(dong)(dong)(dong)(dong)師(shi)(shi)(shi)(shi)范(fan)大(da)(da)學(xue)(xue)(xue)(xue)(xue)駐(zhu)東(dong)(dong)(dong)(dong)明(ming)(ming)(ming)(ming)縣(xian)“第一(yi)(yi)書記(ji)”幫扶東(dong)(dong)(dong)(dong)明(ming)(ming)(ming)(ming)的又一(yi)(yi)重大(da)(da)成果。8月13日，山(shan)(shan)東(dong)(dong)(dong)(dong)師(shi)(shi)(shi)(shi)范(fan)大(da)(da)學(xue)(xue)(xue)(xue)(xue)與東(dong)(dong)(dong)(dong)明(ming)(ming)(ming)(ming)縣(xian)人民政府舉行了教(jiao)育(yu)(yu)合(he)作(zuo)洽談會，之后經過數輪磋商，10月20日，雙方正式簽訂了合(he)作(zuo)辦學(xue)(xue)(xue)(xue)(xue)協議(yi)。根據協議(yi)約定(ding)，東(dong)(dong)(dong)(dong)明(ming)(ming)(ming)(ming)一(yi)(yi)中、縣(xian)一(yi)(yi)初中、縣(xian)三(san)實小分別為山(shan)(shan)師(shi)(shi)(shi)(shi)附中、山(shan)(shan)師(shi)(shi)(shi)(shi)二附中、山(shan)(shan)師(shi)(shi)(shi)(shi)附小的合(he)作(zuo)學(xue)(xue)(xue)(xue)(xue)校(xiao)(xiao)，“山(shan)(shan)東(dong)(dong)(dong)(dong)師(shi)(shi)(shi)(shi)范(fan)大(da)(da)學(xue)(xue)(xue)(xue)(xue)附屬(shu)中學(xue)(xue)(xue)(xue)(xue)東(dong)(dong)(dong)(dong)明(ming)(ming)(ming)(ming)合(he)作(zuo)學(xue)(xue)(xue)(xue)(xue)校(xiao)(xiao)”的揭(jie)牌，標志(zhi)著(zhu)山(shan)(shan)東(dong)(dong)(dong)(dong)師(shi)(shi)(shi)(shi)范(fan)大(da)(da)學(xue)(xue)(xue)(xue)(xue)與東(dong)(dong)(dong)(dong)明(ming)(ming)(ming)(ming)縣(xian)教(jiao)育(yu)(yu)合(he)作(zuo)進入到(dao)了實施階段，雙方教(jiao)育(yu)(yu)合(he)作(zuo)對東(dong)(dong)(dong)(dong)明(ming)(ming)(ming)(ming)縣(xian)教(jiao)育(yu)(yu)發展具有里程碑意義(yi)。
一(yi)中人尊奉(feng)的信念：天行健，君子以自強不息(xi)。
一中人尊奉的校(xiao)訓(xun)：好學(xue)、競爭、團結、文明。
一中人(ren)倡導的校(xiao)風：勤奮、嚴(yan)謹、求實、創新。
一中人遵循的辦學宗旨(zhi)：注(zhu)重素質，全(quan)面發展。
一中人追求的(de)目標：建(jian)成國家重點示范性高中。
一中人(ren)堅信：東(dong)明一中未(wei)來(lai)更(geng)美好，前途更(geng)輝(hui)煌(huang)！
日出東明，黃河湯湯（shangshang）
風流嫻韻，沙沃(wo)里長
百里英才，薈(hui)萃一堂(tang)
春風(feng)化雨(yu)，無限希望
兄弟姐妹(mei)手挽手，孜孜為學惜(xi)韶光
兄(xiong)弟姐妹手挽手，孜(zi)孜(zi)為學惜(xi)韶光(guang)
天行健當自強，莽平原壯肝腸(chang)
天行健(jian)當自強，莽平原壯(zhuang)肝腸
開拓進取為(wei)校爭先，博學創新為(wei)國爭光
開拓進取為校爭先，博學創新(xin)為國爭光。
“東(dong)明(ming)縣第(di)一(yi)中(zhong)(zhong)學(xue)”，定于1958年(nian)(nian)。1970年(nian)(nian)，遷于現(xian)校址。1978年(nian)(nian)，被命(ming)名為(wei)地區重點高中(zhong)(zhong)。東(dong)明(ming)一(yi)中(zhong)(zhong)，乃全日制普通高級(ji)中(zhong)(zhong)學(xue)，現(xian)為(wei)市級(ji)規范化(hua)學(xue)校。東(dong)明(ming)一(yi)中(zhong)(zhong)人才輩出(chu)，桃李遍天下。僅1978年(nian)(nian)到(dao)2002年(nian)(nian)間，就(jiu)有15000多(duo)名畢業生走出(chu)一(yi)中(zhong)(zhong)校門，其中(zhong)(zhong)8700名步入大學(xue)殿堂(tang)，他(ta)們中(zhong)(zhong)的許多(duo)人，正在(zai)海(hai)內外各個(ge)領域，施展著自己的才能，譜寫著生命(ming)的華章。
我心明亮 
