鐵(tie)線蟲(chong)(chong)(chong)(Gordiacea Von Stebold,1843)又名發形蛇(hair snake),亦稱毛細(xi)線蟲(chong)(chong)(chong)(hairworm)或戈爾迪(di)烏斯線蟲(chong)(chong)(chong)(gordian worm),土名為銅絲蛇或天絲。
隸屬(shu)于(yu)線(xian)形動物(wu)門,為鐵線(xian)蟲(chong)綱蠕(ru)蟲(chong)的(de)總稱。與(yu)醫學有關的(de)蟲(chong)種(zhong)分屬(shu)于(yu)鐵線(xian)蟲(chong)目(Gordioidea)、鐵線(xian)蟲(chong)科(ke)(Gordiidae)、鐵線(xian)蟲(chong)屬(shu)(Gordius )和索蟲(chong)科(ke)的(de)Chordodes, Paragordius和Parachordodes屬(shu)等,250~300種(zhong)。鐵線(xian)蟲(chong)體細長,馬鬃狀,長可(ke)(ke)達1米。成蟲(chong)在海水(shui)(shui)或淡水(shui)(shui)中自由生(sheng)(sheng)活,幼蟲(chong)寄(ji)生(sheng)(sheng)在節肢動物(wu)體內。國(guo)內分布于(yu)南北方各省(sheng),國(guo)外廣泛(fan)分布于(yu)世(shi)界各地。可(ke)(ke)通過水(shui)(shui)源感染人體,引起鐵線(xian)蟲(chong)病。在科(ke)研中,常作為動物(wu)學的(de)實驗材料(liao)。
鐵線蟲(chong)見于(yu)熱(re)帶和溫帶,在(zai)水中營自由生活,偶能感染人(ren)體(ti),寄生于(yu)消化道內(nei)。成蟲(chong)呈線狀,雌(ci)雄異(yi)體(ti),雌(ci)蟲(chong)在(zai)水邊(bian)產卵(luan),以(yi)蚱蜢、蟑螂和甲(jia)蟲(chong)等昆蟲(chong)為中間宿主。
大型個體(ti)(ti)。體(ti)(ti)長為300-1000毫米(mi),體(ti)(ti)型似細繩狀。與線(xian)蟲的圓蟲類相(xiang)似,但無背線(xian)、腹線(xian)與側線(xian)。前端(duan)鈍圓,體(ti)(ti)表角質堅硬,雄(xiong)體(ti)(ti)末(mo)端(duan)分(fen)叉,呈(cheng)倒 "V"字形,分(fen)叉部分(fen)的前腹面為泄殖(zhi)孔。消化管幼(you)蟲期(qi)(qi)存在,而成(cheng)蟲期(qi)(qi)則退化。雄(xiong)體(ti)(ti)的精巢和雌體(ti)(ti)的卵巢數目多,成(cheng)對排列于身(shen)體(ti)(ti)的兩側。生活時體(ti)(ti)呈(cheng)深棕色。
成(cheng)(cheng)蟲(chong)棲息于河流、池塘及水溝內,雌體(ti)所產(chan)的卵在水內孵出(chu)幼(you)蟲(chong),被昆蟲(chong)或人類吃進后,通過寄生生活。當這種蟲(chong)被大型(xing)節肢動物如螳螂、蝗蟲(chong)等(deng)吞食后,幼(you)蟲(chong)在這些節肢動物體(ti)內繼續(xu)發(fa)育,會(hui)逐(zhu)漸控制宿(su)主的行(xing)為,幼(you)蟲(chong)成(cheng)(cheng)長為成(cheng)(cheng)蟲(chong)時(shi),會(hui)控制宿(su)主尋找水源(yuan)淹死宿(su)主后從(cong)宿(su)主體(ti)內鉆出(chu)。
人(ren)類很容易在水(shui)池里(li)和(he)(he)不(bu)干(gan)凈的(de)(de)水(shui)里(li)喝(he)到這些鐵線蟲的(de)(de)幼(you)蟲,喝(he)下(xia)去后有一定幾(ji)率感染鐵線蟲病(bing),這種病(bing)會使(shi)尿道感染發炎,所以(yi)池塘的(de)(de)水(shui)和(he)(he)不(bu)干(gan)凈的(de)(de)水(shui)不(bu)能隨(sui)便喝(he)。幼(you)蟲在節肢(zhi)動物(wu)體內會誘使(shi)寄生體去尋找水(shui)源,所以(yi)水(shui)源有節肢(zhi)動物(wu)尸(shi)體的(de)(de)時候(hou),不(bu)建(jian)議(yi)飲用。
成蟲在水中獨自生活,偶(ou)爾感染人體(ti),引起鐵線蟲病(nematomorphiasis)。本病女性(xing)多于男性(xing)。
蟲(chong)體(ti)細長(chang)(chang)(chang),圓(yuan)線形(xing),似鐵絲,黑褐色;長(chang)(chang)(chang)約(yue)10~50cm,寬(kuan)約(yue)1~3mm; 頭端(duan)鈍圓(yuan),具有(you)0.5~1mm長(chang)(chang)(chang)的(de)淡黃色區;蟲(chong)體(ti)表面有(you)許多小乳突(tu);雄蟲(chong)尾部卷曲,末(mo)端(duan)分(fen)叉;雌蟲(chong)尾短尖鈍。蟲(chong)體(ti)在體(ti)外非(fei)常(chang)活躍,常(chang)有(you)自行打結的(de)習性。
鐵線(xian)蟲(chong)(chong)(chong)(chong)(chong)(chong)(chong)成蟲(chong)(chong)(chong)(chong)(chong)(chong)(chong)生(sheng)(sheng)(sheng)活(huo)于沼澤、池(chi)塘、溪流、溝(gou)渠(qu)等水體(ti)中(zhong),雌雄交配產卵,卵內(nei)(nei)幼蟲(chong)(chong)(chong)(chong)(chong)(chong)(chong)孵出(chu)(chu)進(jin)入昆(kun)蟲(chong)(chong)(chong)(chong)(chong)(chong)(chong)(蚱蜢(locust)、蟋(xi)蟀(Cricket)、蟑螂(lang)(Cockroach)、甲蟲(chong)(chong)(chong)(chong)(chong)(chong)(chong)(Beetle)等)體(ti)內(nei)(nei)發(fa)育(yu)形(xing)成稚(zhi)蟲(chong)(chong)(chong)(chong)(chong)(chong)(chong),昆(kun)蟲(chong)(chong)(chong)(chong)(chong)(chong)(chong)入水,稚(zhi)蟲(chong)(chong)(chong)(chong)(chong)(chong)(chong)離開(kai)宿主(zhu)在水中(zhong)發(fa)育(yu)為(wei)成蟲(chong)(chong)(chong)(chong)(chong)(chong)(chong)。人(ren)體(ti)消化道(dao)感染鐵線(xian)蟲(chong)(chong)(chong)(chong)(chong)(chong)(chong)可能是通過接(jie)觸(chu)或(huo)飲用含有稚(zhi)蟲(chong)(chong)(chong)(chong)(chong)(chong)(chong)的(de)(de)生(sheng)(sheng)(sheng)水、昆(kun)蟲(chong)(chong)(chong)(chong)(chong)(chong)(chong)、魚類和螺類或(huo)食物(wu)(wu)而引(yin)起(qi)。尿(niao)路感染是由于人(ren)體(ti)會(hui)陰部接(jie)觸(chu)有鐵線(xian)蟲(chong)(chong)(chong)(chong)(chong)(chong)(chong)稚(zhi)蟲(chong)(chong)(chong)(chong)(chong)(chong)(chong)的(de)(de)水體(ti),經(jing)尿(niao)道(dao)侵(qin)入,上行(xing)至膀胱內(nei)(nei)寄(ji)生(sheng)(sheng)(sheng)。蟲(chong)(chong)(chong)(chong)(chong)(chong)(chong)體(ti)侵(qin)入人(ren)體(ti)后(hou)可進(jin)一(yi)步(bu)發(fa)育(yu)至成蟲(chong)(chong)(chong)(chong)(chong)(chong)(chong),并可存活(huo)數(shu)年。寄(ji)生(sheng)(sheng)(sheng)泌尿(niao)道(dao)的(de)(de)患者,以女性(xing)為(wei)多,均有明顯的(de)(de)泌尿(niao)道(dao)刺激癥(zheng),如下(xia)腹部劇烈疼(teng)痛、尿(niao)頻、尿(niao)急、尿(niao)痛、血尿(niao)、放射性(xing)腰痛、會(hui)陰和陰道(dao)炎等,蟲(chong)(chong)(chong)(chong)(chong)(chong)(chong)體(ti)排出(chu)(chu)后(hou),癥(zheng)狀緩解。鐵線(xian)蟲(chong)(chong)(chong)(chong)(chong)(chong)(chong)寄(ji)生(sheng)(sheng)(sheng)于消化道(dao)所引(yin)起(qi)的(de)(de)癥(zheng)狀一(yi)般不明顯,可有消化不良、腹痛、腹瀉等表現(xian)。亦見(jian)有從眼眶腫物(wu)(wu)或(huo)耳(er)道(dao)檢出(chu)(chu)蟲(chong)(chong)(chong)(chong)(chong)(chong)(chong)體(ti)的(de)(de)報告(gao)。
診斷本病(bing)依(yi)據從(cong)尿中或糞便中檢(jian)獲蟲(chong)體。在臨(lin)床(chuang)上若遇到有尿道(dao)刺激癥狀(zhuang),久治(zhi)不愈、而又有生(sheng)飲或會(hui)陰部接觸過塘、溝(gou)水(shui)或潮濕草地的患者(zhe),應考慮作膀胱(guang)鏡檢(jian)。
鐵(tie)線蟲病盡管是一(yi)種較(jiao)為罕(han)見的寄(ji)生蟲病,全世界只有(you)14個國家有(you)病例報(bao)道。但各(ge)地因生產(chan)生活接(jie)觸自然水體的人群甚多(duo)(duo),其實際感(gan)染(ran)人數(shu)可(ke)能(neng)遠比已報(bao)告的例數(shu)要多(duo)(duo)。
防治本病的關(guan)鍵是不(bu)(bu)飲不(bu)(bu)潔之(zhi)水(shui)(shui)、不(bu)(bu)生吃昆(kun)蟲(chong)(chong)、魚類(lei)和螺類(lei)等食物,下(xia)水(shui)(shui)時避免下(xia)體與(yu)不(bu)(bu)潔水(shui)(shui)體直(zhi)接接觸。疑有(you)感(gan)染者(zhe)可口服驅蟲(chong)(chong)藥促蟲(chong)(chong)排出(chu),寄生于組織內者(zhe)應(ying)手術取蟲(chong)(chong)。
遠離鐵線(xian)蟲疾病(bing)的糾纏最好的方(fang)法就(jiu)是不要(yao)吃生(sheng)的食(shi)(shi)物,魚類(lei),以及螺類(lei)食(shi)(shi)物,這些(xie)都是不太(tai)衛生(sheng)的食(shi)(shi)物。在(zai)飲食(shi)(shi)的時候要(yao)注意看(kan)是否(fou)有與(yu)不干凈的水體有關聯的情況。而(er)且,從臨床方(fang)面數(shu)據也能夠(gou)看(kan)到,被鐵線(xian)蟲糾纏的女性遠遠多(duo)于(yu)男性,所以希望廣(guang)大女性要(yao)重視起來。