先世系江西彭(peng)澤人，曾祖父(fu)曾遜，祖父(fu)曾輝(hui)。父(fu)曾璠(fan)，嘉靖(jing)(jing)四(si)(si)十一(yi)年(nian)(nian)(nian)壬戍科(ke)(ke)進士(shi)(shi)。曾省吾生(sheng)于嘉靖(jing)(jing)十一(yi)年(nian)(nian)(nian)（1532年(nian)(nian)(nian)），嘉靖(jing)(jing)三(san)十五年(nian)(nian)(nian)丙辰科(ke)(ke)進士(shi)(shi)。隆慶末(mo)年(nian)(nian)(nian)，以右(you)僉都御史(shi)巡撫四(si)(si)川，《明史(shi)稿》稱其“嫻將略，善(shan)治邊”，“蒞事精(jing)勤，多(duo)有建白”。萬(wan)歷元年(nian)(nian)(nian)，四(si)(si)川敘(xu)州土司都掌蠻叛亂，曾省吾薦(jian)劉顯率領官兵十四(si)(si)萬(wan)出(chu)征，“克寨六十余(yu)，俘斬四(si)(si)千(qian)六百(bai)名，拓地四(si)(si)百(bai)余(yu)里，得諸葛銅鼓(gu)九十三(san)”。萬(wan)歷三(san)年(nian)(nian)(nian)六月，升兵部右(you)侍郎。
張(zhang)居正死后，曾(ceng)(ceng)省(sheng)(sheng)(sheng)(sheng)吾(wu)(wu)受到牽(qian)連，浙江(jiang)道監察御(yu)史王(wang)(wang)國彈劾(he)曾(ceng)(ceng)省(sheng)(sheng)(sheng)(sheng)吾(wu)(wu)“勾結馮保，相倚為奸”，“送馮保金銀若干(gan)兩(liang)，圖(tu)謀升官(guan)”，戶科給事(shi)中(zhong)(zhong)王(wang)(wang)繼光疏參曾(ceng)(ceng)省(sheng)(sheng)(sheng)(sheng)吾(wu)(wu)“十(shi)(shi)(shi)罪”。高拱(gong)《病榻遺言》說：“隆慶六年(nian)，曾(ceng)(ceng)省(sheng)(sheng)(sheng)(sheng)吾(wu)(wu)授(shou)意其門(men)生(sheng)、戶科給事(shi)中(zhong)(zhong)曹大野彈劾(he)高拱(gong)，并許以高官(guan)厚祿。”。萬(wan)(wan)歷(li)十(shi)(shi)(shi)年(nian)十(shi)(shi)(shi)二(er)月(yue)，被勒(le)令致仕。萬(wan)(wan)歷(li)十(shi)(shi)(shi)二(er)年(nian)四月(yue)，邱橓與錦衣衛都指揮曹應龍、司禮(li)監太監張(zhang)誠(cheng)前往(wang)張(zhang)家(jia)抄家(jia)，張(zhang)居正長(chang)子張(zhang)敬修被屈(qu)打成招，供出(chu)曾(ceng)(ceng)經向曾(ceng)(ceng)省(sheng)(sheng)(sheng)(sheng)吾(wu)(wu)、王(wang)(wang)篆、傅(fu)作舟三家(jia)轉移(yi)、藏匿財產(chan)，約值銀三十(shi)(shi)(shi)萬(wan)(wan)兩(liang)。張(zhang)敬修最后自縊死，臨死前寫下一(yi)絕命書。丘橓派人查封(feng)曾(ceng)(ceng)省(sheng)(sheng)(sheng)(sheng)吾(wu)(wu)等(deng)人家(jia)產(chan)，并將曾(ceng)(ceng)省(sheng)(sheng)(sheng)(sheng)吾(wu)(wu)、王(wang)(wang)篆法辦，“曾(ceng)(ceng)角巾(jin)青衣，王(wang)(wang)直(zhi)囚(qiu)服乞哀，中(zhong)(zhong)官(guan)杖之”。萬(wan)(wan)歷(li)十(shi)(shi)(shi)二(er)年(nian)三月(yue)，工(gong)科給事(shi)中(zhong)(zhong)唐堯欽上書要求重懲曾(ceng)(ceng)省(sheng)(sheng)(sheng)(sheng)吾(wu)(wu)。萬(wan)(wan)歷(li)十(shi)(shi)(shi)二(er)年(nian)十(shi)(shi)(shi)月(yue)，籍沒(mei)家(jia)產(chan)，原籍為民，永不敘用。著有《確庵曾(ceng)(ceng)先生(sheng)西蜀平蠻全(quan)錄(lu)》(北京圖(tu)書館古(gu)籍珍本(ben)叢刊，第(di)9冊，書目文(wen)獻(xian)出(chu)版(ban)社1988年(nian))，《千(qian)弓壩石橋記》等(deng)。
巧笑倩兮 
