2021年(nian)，經合(he)肥(fei)市初步(bu)核算，蜀山區(qu)地區(qu)生產(chan)總值（GDP）為1210.55億(yi)元(yuan)，按(an)可比(bi)(bi)價(jia)格計算，比(bi)(bi)上年(nian)增(zeng)(zeng)長(chang)7.1%。其中，第(di)(di)一產(chan)業(ye)(ye)(ye)增(zeng)(zeng)加(jia)值2.10億(yi)元(yuan)，比(bi)(bi)上年(nian)下降43.1%；第(di)(di)二產(chan)業(ye)(ye)(ye)增(zeng)(zeng)加(jia)值202.93億(yi)元(yuan)，比(bi)(bi)上年(nian)增(zeng)(zeng)長(chang)0.5%；第(di)(di)三產(chan)業(ye)(ye)(ye)增(zeng)(zeng)加(jia)值1005.52億(yi)元(yuan)，比(bi)(bi)上年(nian)增(zeng)(zeng)長(chang)8.7%，三次產(chan)業(ye)(ye)(ye)結(jie)構為0.18:16.76:83.06。

2021年(nian)(nian)(nian)(nian)(nian)(nian)(nian)蜀山區實現農林牧(mu)漁業(ye)(ye)(ye)總(zong)產值(zhi)3.3億(yi)(yi)元(yuan)，比(bi)上年(nian)(nian)(nian)(nian)(nian)(nian)(nian)下降50.5%。2021年(nian)(nian)(nian)(nian)(nian)(nian)(nian)末全(quan)區規模以上工業(ye)(ye)(ye)企業(ye)(ye)(ye)70戶，其中，產值(zhi)超億(yi)(yi)元(yuan)企業(ye)(ye)(ye)26戶，占全(quan)區工業(ye)(ye)(ye)產值(zhi)比(bi)重的92.8%。全(quan)年(nian)(nian)(nian)(nian)(nian)(nian)(nian)資質(zhi)內建(jian)筑業(ye)(ye)(ye)企業(ye)(ye)(ye)142家(jia)，比(bi)上年(nian)(nian)(nian)(nian)(nian)(nian)(nian)減少20家(jia)。全(quan)年(nian)(nian)(nian)(nian)(nian)(nian)(nian)實現建(jian)筑業(ye)(ye)(ye)總(zong)產值(zhi)621.82億(yi)(yi)元(yuan)，比(bi)上年(nian)(nian)(nian)(nian)(nian)(nian)(nian)增長31.2%。全(quan)年(nian)(nian)(nian)(nian)(nian)(nian)(nian)社會消費(fei)品零售總(zong)額666.68億(yi)(yi)元(yuan)，比(bi)上年(nian)(nian)(nian)(nian)(nian)(nian)(nian)增長11.8%。全(quan)年(nian)(nian)(nian)(nian)(nian)(nian)(nian)實現進出口貿易額22.433億(yi)(yi)美元(yuan)，比(bi)上年(nian)(nian)(nian)(nian)(nian)(nian)(nian)增長64.7%。全(quan)年(nian)(nian)(nian)(nian)(nian)(nian)(nian)一般公(gong)共(gong)預算(suan)收入(ru)36.6億(yi)(yi)元(yuan)，比(bi)上年(nian)(nian)(nian)(nian)(nian)(nian)(nian)增長7.4%。