2021年(nian)(nian)，經合肥市(shi)初(chu)步核(he)算(suan)，蜀山區地(di)區生(sheng)產(chan)(chan)總值（GDP）為1210.55億(yi)元(yuan)(yuan)，按可比(bi)價格(ge)計(ji)算(suan)，比(bi)上(shang)年(nian)(nian)增長(chang)7.1%。其中，第(di)一產(chan)(chan)業(ye)增加值2.10億(yi)元(yuan)(yuan)，比(bi)上(shang)年(nian)(nian)下降43.1%；第(di)二(er)產(chan)(chan)業(ye)增加值202.93億(yi)元(yuan)(yuan)，比(bi)上(shang)年(nian)(nian)增長(chang)0.5%；第(di)三產(chan)(chan)業(ye)增加值1005.52億(yi)元(yuan)(yuan)，比(bi)上(shang)年(nian)(nian)增長(chang)8.7%，三次產(chan)(chan)業(ye)結構為0.18:16.76:83.06。

2021年(nian)(nian)蜀山區實(shi)現(xian)農林牧漁業(ye)總(zong)(zong)產(chan)值(zhi)(zhi)3.3億(yi)元(yuan)，比(bi)上(shang)(shang)年(nian)(nian)下降50.5%。2021年(nian)(nian)末全(quan)(quan)(quan)區規模以上(shang)(shang)工業(ye)企業(ye)70戶，其(qi)中(zhong)，產(chan)值(zhi)(zhi)超億(yi)元(yuan)企業(ye)26戶，占全(quan)(quan)(quan)區工業(ye)產(chan)值(zhi)(zhi)比(bi)重的92.8%。全(quan)(quan)(quan)年(nian)(nian)資質內(nei)建筑(zhu)業(ye)企業(ye)142家，比(bi)上(shang)(shang)年(nian)(nian)減(jian)少20家。全(quan)(quan)(quan)年(nian)(nian)實(shi)現(xian)建筑(zhu)業(ye)總(zong)(zong)產(chan)值(zhi)(zhi)621.82億(yi)元(yuan)，比(bi)上(shang)(shang)年(nian)(nian)增長31.2%。全(quan)(quan)(quan)年(nian)(nian)社會消(xiao)費(fei)品零售(shou)總(zong)(zong)額666.68億(yi)元(yuan)，比(bi)上(shang)(shang)年(nian)(nian)增長11.8%。全(quan)(quan)(quan)年(nian)(nian)實(shi)現(xian)進出(chu)口貿易(yi)額22.433億(yi)美元(yuan)，比(bi)上(shang)(shang)年(nian)(nian)增長64.7%。全(quan)(quan)(quan)年(nian)(nian)一般公共(gong)預算收入36.6億(yi)元(yuan)，比(bi)上(shang)(shang)年(nian)(nian)增長7.4%。