2021年，經合肥市初步核(he)算，蜀(shu)山(shan)區(qu)地(di)區(qu)生產(chan)(chan)(chan)總值(zhi)（GDP）為1210.55億(yi)元(yuan)，按(an)可比(bi)(bi)價格(ge)計算，比(bi)(bi)上(shang)年增(zeng)(zeng)長7.1%。其中，第一產(chan)(chan)(chan)業(ye)增(zeng)(zeng)加值(zhi)2.10億(yi)元(yuan)，比(bi)(bi)上(shang)年下降43.1%；第二產(chan)(chan)(chan)業(ye)增(zeng)(zeng)加值(zhi)202.93億(yi)元(yuan)，比(bi)(bi)上(shang)年增(zeng)(zeng)長0.5%；第三產(chan)(chan)(chan)業(ye)增(zeng)(zeng)加值(zhi)1005.52億(yi)元(yuan)，比(bi)(bi)上(shang)年增(zeng)(zeng)長8.7%，三次(ci)產(chan)(chan)(chan)業(ye)結構為0.18:16.76:83.06。

2021年(nian)(nian)(nian)(nian)(nian)(nian)蜀山區(qu)實現(xian)(xian)農林牧漁(yu)業(ye)(ye)總產值3.3億(yi)元，比(bi)(bi)(bi)(bi)上(shang)年(nian)(nian)(nian)(nian)(nian)(nian)下降50.5%。2021年(nian)(nian)(nian)(nian)(nian)(nian)末全區(qu)規模以上(shang)工業(ye)(ye)企(qi)業(ye)(ye)70戶，其(qi)中(zhong)，產值超億(yi)元企(qi)業(ye)(ye)26戶，占全區(qu)工業(ye)(ye)產值比(bi)(bi)(bi)(bi)重的92.8%。全年(nian)(nian)(nian)(nian)(nian)(nian)資質內(nei)建(jian)筑業(ye)(ye)企(qi)業(ye)(ye)142家，比(bi)(bi)(bi)(bi)上(shang)年(nian)(nian)(nian)(nian)(nian)(nian)減少20家。全年(nian)(nian)(nian)(nian)(nian)(nian)實現(xian)(xian)建(jian)筑業(ye)(ye)總產值621.82億(yi)元，比(bi)(bi)(bi)(bi)上(shang)年(nian)(nian)(nian)(nian)(nian)(nian)增(zeng)長31.2%。全年(nian)(nian)(nian)(nian)(nian)(nian)社會消(xiao)費品零售(shou)總額(e)666.68億(yi)元，比(bi)(bi)(bi)(bi)上(shang)年(nian)(nian)(nian)(nian)(nian)(nian)增(zeng)長11.8%。全年(nian)(nian)(nian)(nian)(nian)(nian)實現(xian)(xian)進出口(kou)貿易額(e)22.433億(yi)美元，比(bi)(bi)(bi)(bi)上(shang)年(nian)(nian)(nian)(nian)(nian)(nian)增(zeng)長64.7%。全年(nian)(nian)(nian)(nian)(nian)(nian)一般公共預算收(shou)入36.6億(yi)元，比(bi)(bi)(bi)(bi)上(shang)年(nian)(nian)(nian)(nian)(nian)(nian)增(zeng)長7.4%。