蜂膠的消炎鎮(zhen)痛作用

蜂(feng)膠(jiao)(jiao)是很(hen)好的(de)消炎(yan)(yan)鎮痛劑，用(yong)(yong)(yong)蜂(feng)膠(jiao)(jiao)提(ti)取液治療(liao)大(da)白鼠關節炎(yan)(yan)的(de)實(shi)驗證(zheng)明(ming)蜂(feng)膠(jiao)(jiao)有(you)抗炎(yan)(yan)作用(yong)(yong)(yong)；用(yong)(yong)(yong)甲醇誘導小(xiao)(xiao)鼠關節炎(yan)(yan)和水腫(zhong)(zhong)，然后(hou)用(yong)(yong)(yong)蜂(feng)膠(jiao)(jiao)進行試驗，證(zheng)明(ming)蜂(feng)膠(jiao)(jiao)對這(zhe)兩種炎(yan)(yan)癥均有(you)抗炎(yan)(yan)效果，用(yong)(yong)(yong)蜂(feng)膠(jiao)(jiao)和阿司匹林(0. 2g/kg)對照(zhao)，給大(da)鼠口服(fu)受藥(yao)后(hou)1小(xiao)(xiao)時，將其(qi)后(hou)肢進行人(ren)工誘發(fa)炎(yan)(yan)癥性水腫(zhong)(zhong)，然后(hou)每小(xiao)(xiao)時測(ce)定(ding)其(qi)炎(yan)(yan)癥腫(zhong)(zhong)脹(zhang)的(de)程度，試驗證(zheng)明(ming)，蜂(feng)膠(jiao)(jiao)和阿司匹林對炎(yan)(yan)癥腫(zhong)(zhong)脹(zhang)都有(you)抑制作用(yong)(yong)(yong)，而且它們的(de)抗炎(yan)(yan)作用(yong)(yong)(yong)十(shi)分相似。用(yong)(yong)(yong)二甲苯涂抹小(xiao)(xiao)鼠耳部使(shi)鼠耳腫(zhong)(zhong)脹(zhang)，試驗證(zheng)明(ming)，蜂(feng)膠(jiao)(jiao)抗炎(yan)(yan)作用(yong)(yong)(yong)比“消炎(yan)(yan)痛”強。

蜂膠(jiao)有(you)(you)鎮痛(tong)(tong)作(zuo)用。沈勝利等(1986)選擇(ze)雄(xiong)性小鼠采用電(dian)擊法，試驗結果證明，蜂膠(jiao)對電(dian)擊小鼠尾(wei)根部(bu)具有(you)(you)鎮痛(tong)(tong)作(zuo)用，并(bing)能維(wei)持一(yi)定時(shi)間。峰下哲等(1992)采用給小鼠腹腔注射0.7%乙酸，引起扭曲反應作(zuo)為指標，證明了蜂膠(jiao)經口(kou)飼喂能達到與(yu)消炎(yan)痛(tong)(tong)同等或更強的(de)鎮痛(tong)(tong)效應。

蜂(feng)(feng)膠有很強的(de)抗(kang)潰(kui)(kui)(kui)瘍(yang)(yang)(yang)作用。用五(wu)氧化二砷和(he)咖啡因給(gei)大鼠(shu)造(zao)成(cheng)實驗(yan)性胃(wei)潰(kui)(kui)(kui)瘍(yang)(yang)(yang)，試驗(yan)證明，給(gei)蜂(feng)(feng)膠浸液和(he)甲基尿嘧啶的(de)治療組，其(qi)大白(bai)鼠(shu)潰(kui)(kui)(kui)瘍(yang)(yang)(yang)愈(yu)(yu)合平(ping)均面(mian)積相(xiang)似，均比(bi)對(dui)照(zhao)組(給(gei)水)的(de)潰(kui)(kui)(kui)瘍(yang)(yang)(yang)平(ping)均愈(yu)(yu)合而積小(xiao)得多(duo)，表現為中毒癥(zheng)狀輕，體(ti)重增加，而對(dui)照(zhao)組卻呈現亞急性砷中毒;用粒狀氫氧化鈉將金黃地鼠(shu)背前部(bu)致為實驗(yan)性潰(kui)(kui)(kui)瘍(yang)(yang)(yang)，用蜂(feng)(feng)膠酊涂(tu)抹潰(kui)(kui)(kui)瘍(yang)(yang)(yang)處，與不涂(tu)藥處對(dui)照(zhao)，其(qi)結果證明，蜂(feng)(feng)膠酊能促進(jin)潰(kui)(kui)(kui)瘍(yang)(yang)(yang)愈(yu)(yu)合，縮短病(bing)程1/2一(yi)1/3。從病(bing)理學(xue)鏡檢觀察，蜂(feng)(feng)膠確有消(xiao)炎，促進(jin)組織修復的(de)功效。用濃乙酸(suan)對(dui)雄(xiong)性大白(bai)鼠(shu)胃(wei)壁(bi)造(zao)成(cheng)潰(kui)(kui)(kui)瘍(yang)(yang)(yang)，實驗(yan)證明，蜂(feng)(feng)膠有愈(yu)(yu)合作用，不僅潰(kui)(kui)(kui)瘍(yang)(yang)(yang)愈(yu)(yu)合率明顯高于對(dui)照(zhao)組，而且潰(kui)(kui)(kui)瘍(yang)(yang)(yang)面(mian)積縮小(xiao)和(he)病(bing)理組織學(xue)改變亦有明顯差別。