繼發性甲亢是什么意思
繼(ji)發性甲(jia)狀腺(xian)功(gong)能(neng)亢(kang)進癥,是指甲(jia)狀腺(xian)沒有(you)發生病變,不是甲(jia)狀腺(xian)本身的疾病導致,而是由于身體其他部(bu)位出現問(wen)題,使甲(jia)狀腺(xian)激(ji)素(su)合成分泌增多,導致甲(jia)狀腺(xian)功(gong)能(neng)亢(kang)進,可(ke)見(jian)于妊娠、藥物、腫(zhong)瘤等因(yin)素(su)。
繼發性甲亢是什么原因引起的
1、妊娠
妊娠期女性體內HCG含量較高,由于HCG與促甲狀腺激素有部分結構相似,可能會激動受體細胞促進甲狀腺激素分泌,從而導致繼發性甲狀腺功能亢進癥。
2、藥物
甲狀(zhuang)(zhuang)腺(xian)(xian)功(gong)(gong)(gong)(gong)能(neng)(neng)減退時,如果(guo)使(shi)用外源性(xing)甲狀(zhuang)(zhuang)腺(xian)(xian)激素過(guo)多,導致體(ti)內甲狀(zhuang)(zhuang)腺(xian)(xian)激素含量(liang)超過(guo)正(zheng)(zheng)常范圍,機體(ti)產(chan)生藥(yao)物(wu)性(xing)甲狀(zhuang)(zhuang)腺(xian)(xian)功(gong)(gong)(gong)(gong)能(neng)(neng)亢(kang)進癥(zheng)(zheng),也(ye)是繼發性(xing)甲狀(zhuang)(zhuang)腺(xian)(xian)功(gong)(gong)(gong)(gong)能(neng)(neng)亢(kang)進癥(zheng)(zheng)。這時,只要遵醫囑減少左甲狀(zhuang)(zhuang)腺(xian)(xian)素鈉的用量(liang),逐漸使(shi)體(ti)內甲狀(zhuang)(zhuang)腺(xian)(xian)激素的水(shui)平恢復正(zheng)(zheng)常,甲狀(zhuang)(zhuang)腺(xian)(xian)功(gong)(gong)(gong)(gong)能(neng)(neng)亢(kang)進癥(zheng)(zheng)的癥(zheng)(zheng)狀(zhuang)(zhuang)可逐漸消失。
3、腫瘤
常(chang)見于下丘腦垂體病變,如(ru)垂體促甲(jia)(jia)狀(zhuang)(zhuang)(zhuang)腺(xian)(xian)激素(su)(su)瘤,會使促甲(jia)(jia)狀(zhuang)(zhuang)(zhuang)腺(xian)(xian)激素(su)(su)分(fen)泌增多,導致甲(jia)(jia)狀(zhuang)(zhuang)(zhuang)腺(xian)(xian)激素(su)(su)合成增多,出現繼(ji)發性甲(jia)(jia)狀(zhuang)(zhuang)(zhuang)腺(xian)(xian)功(gong)能亢進癥(zheng)。只要將(jiang)病變部(bu)位治(zhi)愈后,甲(jia)(jia)狀(zhuang)(zhuang)(zhuang)腺(xian)(xian)激素(su)(su)水平(ping)可以逐漸恢復正常(chang)。一(yi)些肺癌(ai)患(huan)者,可能出現甲(jia)(jia)狀(zhuang)(zhuang)(zhuang)腺(xian)(xian)激素(su)(su)的分(fen)泌增多,也屬于繼(ji)發性甲(jia)(jia)狀(zhuang)(zhuang)(zhuang)腺(xian)(xian)功(gong)能亢進癥(zheng)。當肺癌(ai)得到控制或(huo)者進行靶(ba)向治(zhi)療后,甲(jia)(jia)狀(zhuang)(zhuang)(zhuang)腺(xian)(xian)功(gong)能亢進癥(zheng)的癥(zheng)狀(zhuang)(zhuang)(zhuang)可以逐漸緩(huan)解。
4、甲狀腺炎
部分甲狀腺炎可能導致T3、T4增(zeng)多,出現(xian)繼發性甲狀腺功(gong)能亢(kang)進癥。當患者出現(xian)疾病(bing)后,要及時到醫(yi)院的內分泌科就診(zhen),以免延誤(wu)病(bing)情。
繼發性甲亢會突眼嗎
繼(ji)發(fa)性(xing)甲(jia)亢(kang)也(ye)是會(hui)有突(tu)(tu)眼(yan)(yan),因為(wei)繼(ji)發(fa)性(xing)甲(jia)亢(kang)患者也(ye)存在著交(jiao)感神經過度(du)興奮。交(jiao)感神經過度(du)興奮,就會(hui)引起突(tu)(tu)眼(yan)(yan),這時候(hou)患者的眼(yan)(yan)睛(jing)突(tu)(tu)出,雙(shuang)目炯炯有神,瞬(shun)目減少(shao),雙(shuang)眼(yan)(yan)往(wang)上(shang)看的時候(hou),額紋(wen)不能(neng)抬起,這種突(tu)(tu)眼(yan)(yan)稱(cheng)為(wei)良性(xing)突(tu)(tu)眼(yan)(yan)。治療這種突(tu)(tu)眼(yan)(yan)不需(xu)要特殊治療眼(yan)(yan)睛(jing),只需(xu)要把甲(jia)亢(kang)控制好(hao)就可以了,當(dang)甲(jia)狀腺功能(neng)逐漸恢復正常,這種良性(xing)突(tu)(tu)眼(yan)(yan)就會(hui)逐漸的恢復。
繼(ji)發性(xing)甲亢(kang)很少會出(chu)現惡性(xing)突眼,所以大部分的繼(ji)發性(xing)甲亢(kang)患(huan)者突眼都(dou)會得(de)到(dao)緩解。
繼發性甲亢和原發性甲亢區別
1、發病原理
原(yuan)發性甲(jia)(jia)狀(zhuang)(zhuang)腺(xian)(xian)(xian)(xian)(xian)(xian)功能(neng)亢(kang)進癥(zheng)的發病(bing)部(bu)位為甲(jia)(jia)狀(zhuang)(zhuang)腺(xian)(xian)(xian)(xian)(xian)(xian),由(you)于甲(jia)(jia)狀(zhuang)(zhuang)腺(xian)(xian)(xian)(xian)(xian)(xian)病(bing)變造成(cheng)甲(jia)(jia)狀(zhuang)(zhuang)腺(xian)(xian)(xian)(xian)(xian)(xian)激素合成(cheng)與分泌增多,機體出現甲(jia)(jia)狀(zhuang)(zhuang)腺(xian)(xian)(xian)(xian)(xian)(xian)功能(neng)亢(kang)進癥(zheng)。而繼發性甲(jia)(jia)狀(zhuang)(zhuang)腺(xian)(xian)(xian)(xian)(xian)(xian)功能(neng)亢(kang)進癥(zheng)是(shi)由(you)于甲(jia)(jia)狀(zhuang)(zhuang)腺(xian)(xian)(xian)(xian)(xian)(xian)以(yi)外的組(zu)織發生(sheng)病(bing)變,刺激甲(jia)(jia)狀(zhuang)(zhuang)腺(xian)(xian)(xian)(xian)(xian)(xian)組(zu)織增生(sheng),進而產生(sheng)過(guo)多的甲(jia)(jia)狀(zhuang)(zhuang)腺(xian)(xian)(xian)(xian)(xian)(xian)激素,發生(sheng)甲(jia)(jia)狀(zhuang)(zhuang)腺(xian)(xian)(xian)(xian)(xian)(xian)功能(neng)亢(kang)進癥(zheng)。
2、激素水平
促甲(jia)狀(zhuang)腺(xian)激素(su)與(yu)甲(jia)狀(zhuang)腺(xian)激素(su)之間為負反饋(kui)調節機(ji)制,對于原發(fa)(fa)性甲(jia)狀(zhuang)腺(xian)功能亢(kang)進(jin)癥(zheng)(zheng)患者來說,甲(jia)狀(zhuang)腺(xian)激素(su)升(sheng)高(gao),抑制促甲(jia)狀(zhuang)腺(xian)激素(su)的釋放和分泌,造(zao)成促甲(jia)狀(zhuang)腺(xian)激素(su)水(shui)(shui)平(ping)數值(zhi)較低。而繼發(fa)(fa)性甲(jia)狀(zhuang)腺(xian)功能亢(kang)進(jin)癥(zheng)(zheng)多(duo)數是由于下丘腦或垂體(ti)發(fa)(fa)生炎(yan)癥(zheng)(zheng)、腫(zhong)瘤等(deng)因素(su),引起促甲(jia)狀(zhuang)腺(xian)激素(su)水(shui)(shui)平(ping)明顯升(sheng)高(gao),同時甲(jia)狀(zhuang)腺(xian)激素(su)水(shui)(shui)平(ping)合成、分泌增多(duo),這時血液檢查促甲(jia)狀(zhuang)腺(xian)激素(su)、甲(jia)狀(zhuang)腺(xian)激素(su)的水(shui)(shui)平(ping)均在高(gao)水(shui)(shui)平(ping)狀(zhuang)態(tai)。
3、治療原則
原發性甲狀腺功能亢進癥主要針對原發病進行治療,繼發性甲狀腺功能亢進(jin)癥(zheng)的患者一般針對下丘腦或(huo)垂體進(jin)行針對性的治療。
4、臨床表現
原發性甲狀腺(xian)功(gong)能(neng)亢(kang)進癥的(de)(de)患(huan)者通常發病較迅速,且會出(chu)(chu)現突眼癥狀,而繼發性甲狀腺(xian)功(gong)能(neng)亢(kang)進癥的(de)(de)患(huan)者病程(cheng)相對較慢,且較少(shao)出(chu)(chu)現突眼癥狀。但(dan)均(jun)可出(chu)(chu)現高(gao)代謝癥候群,主要包括(kuo)心慌、出(chu)(chu)汗、消瘦、食欲亢(kang)進等(deng),由(you)于神經肌肉的(de)(de)興奮(fen)性增高(gao),患(huan)者還可出(chu)(chu)現手抖、雙手震顫等(deng)癥狀,應(ying)及時就醫進行鑒別診斷(duan)。